Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602053 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5603850 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5603666 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5602730 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5603205 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5602538 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL5602365 | 0.98 | — | — | |
| SCHEMBL5602823 | 0.89 | — | — | |
| SCHEMBL28819357 | 0.64 | — | — | |
| SCHEMBL16911826 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |