SCHEMBL5604264

SCHEMBL5604264

CC1=CC(C)=C([Si](C)(C)C2=C(C)C=C(C)C2)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4810229 0.95
SCHEMBL1823804 0.80
SCHEMBL8190242 0.75
Hydrochloric Acid SCHEMBL4816927 0.69
SCHEMBL10319448 0.69 KDM4E (0.31)
SCHEMBL1027102 0.65
SCHEMBL8157414 0.65
SCHEMBL4652308 0.65
SCHEMBL9142020 0.63
SCHEMBL8779676 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756609-A Homogeneous metallocene-based olefin polymerization system with increased activity AMOCO CORPORATION (US) 1998-05-26 US claimed
WO-1997014727-A1 HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY AMOCO CORPORATION (US) 1997-04-24 WO claimed
EP-1761572-A1 OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF A RADICAL GENERATING SYSTEM INNOVENE INC. (US) 2007-03-14 EP disclosed
WO-2006012246-A1 OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF A RADICAL GENERATING SYSTEM INNOVENE INC. (US) 2006-02-02 WO disclosed
EP-0834515-B1 New Organotransition Metal Compounds KANTO KAGAKU (JP) 2004-02-25 EP disclosed
US-5859276-A Organotransition metal compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 1999-01-12 US disclosed
US-5756609-A Homogeneous metallocene-based olefin polymerization system with increased activity AMOCO CORPORATION (US) 1998-05-26 US disclosed
EP-0834515-A2 Transition-metal containing organic compounds and their use as catalysts for olefin polymerization KANTO KAGAKU KABUSHIKI KAISHA (JP) 1998-04-08 EP disclosed
WO-1997014727-A1 HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY AMOCO CORPORATION (US) 1997-04-24 WO disclosed