SCHEMBL5604286

SCHEMBL5604286

OCCCCCCC1CC2C=CC1C2

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.39
ALDH1A1 P00352 4/20 0.39
EPHX2 P34913 2/20 0.36
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 3/20 0.33
HTT P42858 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
USP2 O75604 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13346630 1.00 KDM4E (0.39) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL13346631 1.00 KDM4E (0.39) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL13346629 1.00 KDM4E (0.39) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL13346627 1.00 KDM4E (0.39) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL2513013 0.98 KDM4E (0.40) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL2979672 0.92 KDM4E (0.41) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL30996063 0.90 KDM4E (0.44) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL4445579 0.90 KDM4E (0.44) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL1975023 0.88 KDM4E (0.46) KDM4EALDH1A1EPHX2TSHRTDP1
SCHEMBL17934495 0.84 KDM4E (0.43) KDM4EALDH1A1EPHX2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed
EP-0997482-B1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO (JP) 2007-01-17 EP disclosed
US-6346581-B1 CURABLE COMPOSITION COMPRISING POLYMER OBTAINED BY INTRODUCING FUNCTIONAL GROUP INTO CYCLOOLEFIN ADDITION POLYMER CONSISTING OF UNITS DERIVED FROM CYCLOOLEFIN MONOMERS WITH AND WITHOUT SIDE CHAIN HAVING 4 OR MORE CARBONS, HARDENING AGENT NIPPON ZEON CO., LTD (JP) 2002-02-12 US disclosed
EP-0997482-A1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 2000-05-03 EP disclosed