SCHEMBL5604335

SCHEMBL5604335

CCCC(O)C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370548 0.85 KDM4E (0.36) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL11732491 0.83 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL4666821 0.82 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL2040045 0.81 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL7232965 0.79 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL7895971 0.79 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL13370896 0.79 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL5604510 0.78 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL31396475 0.78 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL6837049 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0997482-B1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO (JP) 2007-01-17 EP disclosed
US-6346581-B1 CURABLE COMPOSITION COMPRISING POLYMER OBTAINED BY INTRODUCING FUNCTIONAL GROUP INTO CYCLOOLEFIN ADDITION POLYMER CONSISTING OF UNITS DERIVED FROM CYCLOOLEFIN MONOMERS WITH AND WITHOUT SIDE CHAIN HAVING 4 OR MORE CARBONS, HARDENING AGENT NIPPON ZEON CO., LTD (JP) 2002-02-12 US disclosed
EP-0997482-A1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 2000-05-03 EP disclosed
US-4033982-A REACTING NORBORNENES WITH SULFUR GENERAL ELECTRIC COMPANY (US) 1977-07-05 US disclosed