Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206705 | 0.87 | F10 (0.48) | F10MAPT | |
| SCHEMBL5605023 | 0.84 | F10 (0.57) | F10MAPTTDP1ALDH1A1PTGS2 | |
| SCHEMBL85602 | 0.80 | F10 (0.55) | F10ALDH1A1 | |
| SCHEMBL75813 | 0.79 | NPC1 (0.63) | F10LMNAALDH1A1PTGS2 | |
| SCHEMBL8269738 | 0.79 | NPC1 (0.63) | F10LMNAALDH1A1PTGS2 | |
| SCHEMBL76617 | 0.78 | F10 (0.73) | F10MAPTPTGS2 | |
| SCHEMBL76106 | 0.78 | F10 (0.73) | F10MAPTPTGS2 | |
| SCHEMBL76591 | 0.78 | F10 (0.73) | F10MAPTPTGS2 | |
| SCHEMBL76592 | 0.78 | F10 (0.73) | F10MAPTPTGS2 | |
| SCHEMBL76107 | 0.78 | F10 (0.73) | F10MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791597-A2 | CARBONYL COMPOUND-CONTAINING DRUG AND THE USE THEREOF | Merck Patent GmbH (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006032342-A2 | CARBONYL COMPOUND-CONTAINING DRUG AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2006-03-30 | — | — | WO | disclosed |