Acetoacetic Acid

Acetoacetic Acid

SCHEMBL5605563

C=COC(=O)CC(C)=O.CC(=O)CC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
LMNA P02545 1/20 0.31
SLC15A2 Q16348 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27553962 0.91 MGAM (0.48) MGAMGAASIMGAM2KDM4E
SCHEMBL94026 0.91
Methacrylic Acid SCHEMBL29058849 0.86 MGAM (0.43) MGAMGAASIMGAM2KDM4E
Acetoacetic Acid SCHEMBL27553963 0.85 KDM4E (0.37) MGAMGAASIMGAM2KDM4E
SCHEMBL28813485 0.85 MGAM (0.46) MGAMGAASIMGAM2LMNA
SCHEMBL1309191 0.84
Acetic Acid SCHEMBL27803441 0.82 FFAR3 (0.35) MGAMGAASIMGAM2HSD17B10
Acetoacetic Acid SCHEMBL9184451 0.80 KDM4E (0.39) MGAMGAASIMGAM2KDM4E
Acetoacetic Acid SCHEMBL1318189 0.80 TSHR (0.44) MGAMGAASIMGAM2KDM4E
Acetoacetic Acid SCHEMBL14800067 0.79 TSHR (0.43) MGAMGAASIMGAM2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007056262-A2 POLYMER COMPOSITIONS HAVING NOVEL CURE SYSTEMS AND METHOD OF MAKING ARTICLES WITH SAME DOW REICHHOLD SPECIALTY LATEX, LLC (US) 2007-05-18 WO disclosed
US-20070100081-A1 Polymer compositions having novel cure systems and method of making articles with same DOW REICHHOLD SPECIALTY LATEX LLC 2007-05-03 US disclosed
EP-1355964-B1 POLYMERS HAVING CURE SYSTEM REICHHOLD INC (US) 2005-03-30 EP disclosed
EP-1355964-A2 POLYMERS HAVING NOVEL CURE SYSTEM Reichhold, Inc. (US) 2003-10-29 EP disclosed
US-6624274-B1 Curable conjugated diene copolymer with chelating monomer; sulfur-free DOW REICHHOLD SPECIALTY LATEX LLC 2003-09-23 US disclosed
US-20030155681-A1 Pulverulent binder composition WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2003-08-21 US disclosed
US-20020117815-A1 Gaskets utilizing polymers having a novel cure system REICHHOLD, INC. 2002-08-29 US disclosed
WO-2002038640-A2 POLYMERS HAVING NOVEL CURE SYSTEM REICHHOLD, INC. (US) 2002-05-16 WO disclosed
US-4397968-A MEASURED ADDITION OF MONOMERS TO AQUEOUS POLYVINYL ALCOHOL WACKER-CHEMIE GMBH (DE) 1983-08-09 US disclosed