Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MPO | P05164 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL17889024 | 1.00 | KDM4E (0.67) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL5605980 | 1.00 | KDM4E (0.67) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL1833538 | 0.97 | KDM4E (0.63) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL1833542 | 0.97 | KDM4E (0.63) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28813398 | 0.96 | KDM4E (0.61) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27630530 | 0.96 | KDM4E (0.61) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27662421 | 0.96 | KDM4E (0.61) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL9397492 | 0.96 | KDM4E (0.61) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27753251 | 0.95 | KDM4E (0.60) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL3972882 | 0.95 | KDM4E (0.60) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802287-A2 | MINICAPSULE FORMULATIONS | Sigmoid Biotechnologies Limited (IE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006035416-A2 | MINICAPSULE FORMULATIONS | SIGMOID BIOTECHNOLOGIES LIMITED (IE) | 2006-04-06 | — | — | WO | disclosed |