SCHEMBL5606077

SCHEMBL5606077

C=CCCCCCC.CCO[SiH](OCC)OCC

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.67
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.37
FAAH O00519 2/20 0.34
TRPV1 Q8NER1 1/20 0.34
ABCC4 O15439 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28558612 0.91 TSHR (0.64) TSHRALDH1A1LMNA
SCHEMBL1230222 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1228861 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1229923 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL8513813 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1229771 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1229769 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL8514062 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1230561 0.86 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL1229121 0.83 TSHR (0.44) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608480-B Asymmetric silicone oil and preparation method and application thereof 万华化学集团股份有限公司 2022-08-02 CN claimed
CN-112608480-A Asymmetric silicone oil and preparation method and application thereof 万华化学集团股份有限公司 2021-04-06 CN claimed
CN-112608480-B Asymmetric silicone oil and preparation method and application thereof 万华化学集团股份有限公司 2022-08-02 CN disclosed
CN-112608480-A Asymmetric silicone oil and preparation method and application thereof 万华化学集团股份有限公司 2021-04-06 CN disclosed
CN-105916869-B Co catalysts and they be used for hydrosilylation and dehydrogenation silanization purposes 莫门蒂夫性能材料股份有限公司 2019-11-22 CN disclosed
CN-108026126-A Use dehydrogenation silanization, hydrosilylation and the crosslinking of pyridine diimine carboxylic acid Co catalysts 莫门蒂夫性能材料股份有限公司 2018-05-11 CN disclosed
CN-105916869-A Cobalt catalysts and their use for hydrosilylation and dehydrogenative silylation 莫门蒂夫性能材料股份有限公司 2016-08-31 CN disclosed
CN-105498843-A Preparation method of porous ceramic-carried platinum catalyst HANGZHOU LEYI NEW MAT TECH CO LTD 2016-04-20 CN disclosed
CN-101560221-B Concrete surface penetration silane low polymer and preparation method thereof NANJING HYDRAULIC RES INSTITUE THE MINISTRY OF WATER RESOURCES THE MINISTRY OF COMMUNICATIONS AND TH 2012-03-28 CN disclosed
CN-101560221-A Concrete surface penetration silane low polymer and preparation method thereof NANJING HYDRAULIC RES INST MWR (CN) 2009-10-21 CN disclosed
US-7241824-B2 Rubber composition for a tire comprising a coupling agent (white filler/diene elastomer) activated by a heat-triggered radical initiator MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2007-07-10 US disclosed
US-20040249048-A1 Rubber composition for a tire comprising a coupling agent (white filler/diene elastomer) activated by a heat-triggered radical initiator MICHELIN RECHERCHE ET TECHNIQUE, S.A. (CH) 2004-12-09 US disclosed
EP-1265956-B1 RUBBER COMPOSITION FOR A TYRE, COMPRISING A COUPLING AGENT (WHITE FILLER/DIENIC ELASTOMER) ACTIVATED BY A HEAT-INITIATED RADICAL STARTER MICHELIN SOC TECH (FR) 2003-10-22 EP disclosed
CN-1414993-A Rubber composition for tyres containing a coupling agent (white filler/diene elastomer) activated by a thermal braking radical initiator MICHELIN RECH TECH (FR) 2003-04-30 CN disclosed
EP-1265956-A1 RUBBER COMPOSITION FOR A TYRE, COMPRISING A COUPLING AGENT (WHITE FILLER/DIENIC ELASTOMER) ACTIVATED BY A HEAT-INITIATED RADICAL STARTER Société de Technologie Michelin (FR) 2002-12-18 EP disclosed
WO-2001049781-A1 RUBBER COMPOSITION FOR A TYRE, COMPRISING A COUPLING AGENT (WHITE FILLER/DIENIC ELASTOMER) ACTIVATED BY A HEAT-INITIATED RADICAL STARTER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2001-07-12 WO disclosed