Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728661 | 0.82 | LCK (0.79) | LCK | |
| SCHEMBL773665 | 0.82 | LCK (0.62) | LCKMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL775124 | 0.81 | LCK (0.69) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL774069 | 0.79 | LCK (0.67) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14568765 | 0.79 | LCK (0.73) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27562404 | 0.79 | LCK (0.77) | LCKMAPT | |
| SCHEMBL14568779 | 0.78 | SMN1; SMN2 (0.68) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22824733 | 0.77 | LCK (0.58) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22824734 | 0.77 | LCK (0.58) | LCKMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14568750 | 0.76 | LCK (1.00) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758564-A2 | SYNERGISTIC METHODS AND COMPOSITIONS FOR TREATING CANCER | Brystol-Myers Squibb Company (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005094376-A2 | SYNERGISTIC METHODS AND COMPOSITIONS FOR TREATING CANCER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-10-13 | — | — | WO | disclosed |