Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897557 | 0.91 | TSHR (0.56) | TSHRHPGDHCAR2THRBATM | |
| SCHEMBL5133477 | 0.90 | TSHR (0.50) | TSHRHPGDHCAR2THRBATM | |
| SCHEMBL5051102 | 0.89 | HPGD (0.37) | TSHRHPGDHCAR2THRB | |
| SCHEMBL6035615 | 0.88 | TSHR (0.38) | TSHRHPGDHCAR2THRBATM | |
| Acrylic Acid Ethyl Ester SCHEMBL17956576 | 0.88 | TSHR (0.52) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Methacrylic Acid SCHEMBL8025755 | 0.87 | TSHR (0.51) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL6895973 | 0.86 | HCAR2 (0.43) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL5054808 | 0.85 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL6706229 | 0.84 | TSHR (0.46) | TSHRHPGDHCAR2THRBATM | |
| Acrylic Acid Methyl Ester SCHEMBL17956580 | 0.83 | TSHR (0.49) | TSHRHPGDHCAR2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273842-B1 | Colorants, dispersants and dispersions containing polymeric nanoparticles | ROHM AND HAAS COMPANY (US) | 2007-09-25 | — | — | US | disclosed |