Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607763 | 0.95 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5607593 | 0.93 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5606889 | 0.93 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5607928 | 0.92 | PIK3CG (0.41) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5607509 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL4764454 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5607427 | 0.91 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5259222 | 0.91 | PIK3CD (0.40) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL5607940 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CB | |
| SCHEMBL5607167 | 0.90 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750715-A1 | METHODS FOR TREATING MAST CELL DISORDERS | ICOS CORPORATION (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005120511-A1 | METHODS FOR TREATING MAST CELL DISORDERS | ICOS CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |