SCHEMBL5608239

SCHEMBL5608239

O=C1C=CC=C2C=CC=C2C1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28417767 0.94 GSK3A (0.35) GSK3AGSK3B
SCHEMBL28422795 0.91 GSK3A (0.36) GSK3AGSK3B
SCHEMBL8722677 0.81
SCHEMBL27990953 0.79
SCHEMBL14005661 0.73 GSK3A (0.31) GSK3AGSK3B
SCHEMBL28562655 0.73
SCHEMBL7233598 0.69 GSK3A (0.32) GSK3AGSK3B
SCHEMBL27823103 0.67
SCHEMBL27651405 0.65
SCHEMBL14844714 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3472171-A1 SUBSTITUTED TRICYCLIC HERTEOCYCLIC COMPOUNDS AND USE THEREOF Suzhou Yabao Pharmaceutical R&D Co., Ltd. (CN) 2019-04-24 EP disclosed
WO-2017215600-A1 SUBSTITUTED TRICYCLIC HERTEOCYCLIC COMPOUNDS AND USE THEREOF SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD. (CN) 2017-12-21 WO disclosed
EP-1809297-A1 IMIDAZO[1,5A]TRIAZOLO[1,5D]BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DISORDERS F. Hoffmann-Roche AG (CH) 2007-07-25 EP disclosed
WO-2006040038-A1 IMIDAZO [1, 5-A]TRIAZOLO[1, 5-D]BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DISORDERS F.HOFFMANN-LA ROCHE AG (CH) 2006-04-20 WO disclosed