Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330899 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL13900107 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5608369 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3654228 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3654226 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL10078437 | 1.00 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3657470 | 0.91 | ABL1 (0.52) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3657471 | 0.91 | ABL1 (0.52) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3658551 | 0.91 | ABL1 (0.52) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL3761289 | 0.91 | ABL1 (0.52) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2960164-B2 | — | — | 1999-10-06 | — | — | JP | claimed |
| US-5587480-A | TREATING HIV AND HEPATITIS VIRUS INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 1996-12-24 | — | — | US | claimed |
| EP-0560794-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 1996-09-18 | — | — | EP | claimed |
| EP-0560794-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. | IAF BIOCHEM INT (CA) | 1993-09-22 | — | — | EP | claimed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | claimed |
| EP-1473294-B1 | Substituted 1,3-oxathiolanes with antiviral properties | SHIRE BIOCHEM INC (CA) | 2007-04-18 | — | — | EP | disclosed |
| EP-1473294-A2 | Substituted 1,3-oxathiolanes with antiviral properties | Shire Biochem Inc. (CA) | 2004-11-03 | — | — | EP | disclosed |
| EP-1153924-B1 | Substituted 1,3-oxathiolanes with antiviral properties | SHIRE BIOCHEM INC (CA) | 2004-09-01 | — | — | EP | disclosed |
| US-6369066-B1 | HIV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-04-09 | — | — | US | disclosed |
| EP-0756595-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | SHIRE BIOCHEM INC (CA) | 2002-03-06 | — | — | EP | disclosed |
| EP-1153924-A2 | Substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC (CA) | 2001-11-14 | — | — | EP | disclosed |
| US-6228860-B1 | ADMINISTERING TO TREAT HUMAN IMMUNODEFICIENCY OR HEPATITIS VIRUS INFECTIONS IN MAMMALS RESISTANT TO 3TC OR FTC | BIOCHEM PHARMA INC. (CA) | 2001-05-08 | — | — | US | disclosed |
| US-5587480-A | TREATING HIV AND HEPATITIS VIRUS INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 1996-12-24 | — | — | US | disclosed |
| EP-0560794-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 1996-09-18 | — | — | EP | disclosed |
| EP-0560794-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. | IAF BIOCHEM INT (CA) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | disclosed |