Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.68 |
| ▸ | MC3R | P41968 | 5/20 | 0.68 |
| ▸ | MC5R | P33032 | 4/20 | 0.61 |
| ▸ | PRCP | P42785 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577115 | 0.95 | MC4R (0.74) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4577254 | 0.86 | MC4R (0.73) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4955655 | 0.86 | MC4R (0.73) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4577263 | 0.85 | MC4R (0.63) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4577231 | 0.83 | PRCP (0.63) | MC4RMC3RPRCP | |
| SCHEMBL91100 | 0.83 | MC4R (0.82) | MC4RMC3RMC5RPRCP | |
| SCHEMBL70501 | 0.83 | MC4R (0.82) | MC4RMC3RMC5RPRCP | |
| SCHEMBL31737049 | 0.83 | MC4R (0.82) | MC4RMC3RMC5RPRCP | |
| SCHEMBL63838 | 0.83 | MC4R (0.82) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4955821 | 0.83 | MC4R (0.82) | MC4RMC3RMC5RPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807102-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND SEXUAL DYSFUNCTION | Merck & Co., Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006049933-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND SEXUAL DYSFUNCTION | MERCK & CO., INC. (US) | 2006-05-11 | — | — | WO | disclosed |