Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659570 | 0.88 | HPRT1 (0.54) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL2883786 | 0.84 | NR4A1 (0.52) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL6050386 | 0.83 | NR4A1 (0.61) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL29414437 | 0.81 | CDC25B (0.80) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL29494693 | 0.81 | NR4A1 (0.71) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL244802 | 0.81 | CDC25B (0.80) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL7218991 | 0.81 | NR4A1 (0.71) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL657598 | 0.81 | KDM4E (0.67) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| Naphthoic Acid SCHEMBL17258 | 0.79 | NR4A1 (1.00) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL57618 | 0.79 | NR4A1 (0.68) | NR4A1NR4A2NR4A3MMP3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3162 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9935269-B2 | Electroluminescence element | Konica Minolta, Inc. (JP) | 2018-04-03 | — | — | US | claimed |
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-1790639-B1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2014-03-26 | — | — | EP | claimed |
| US-8530662-B2 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2013-09-10 | — | — | US | claimed |
| US-8242118-B2 | Arylsulfonamide derivatives for use as CCR3 antagonists in the treatment of inflammatory and immunological disorders | AXIKIN PHARMACEUTICALS INC. (US) | 2012-08-14 | — | — | US | claimed |
| EP-2049502-B1 | 2,4-SUBSTITUTED QUINAZOLINES AS LIPID KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-04 | — | — | EP | claimed |
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| US-8053457-B2 | 3-imidazolyl-indoles for the treatment of proliferative diseases | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | claimed |
| EP-2378880-A1 | USE OF 5-PYRIDIN-4YL(1,3)THIAZOLE FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-10-26 | — | — | EP | claimed |
| US-7951816-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-05-31 | — | — | US | claimed |
| EP-0345750-A2 | Polyfunctional protease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | claimed |
| US-4814445-A | ETHERIFICATION, ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-03-21 | — | — | US | claimed |
| US-4803212-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1989-02-07 | — | — | US | claimed |
| US-4707494-A | ANALGESICS, ANTIPYRETICS | E. R. SQUIBB & SONS, INC. (US) | 1987-11-17 | — | — | US | claimed |
| US-4661479-A | ENZYME INHIBITORS | MERCK AND CO., INC. (US) | 1987-04-28 | — | — | US | claimed |
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | claimed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | claimed |
| US-4292238-A | Alkylation of benzthiazole-azo-phenylamine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | claimed |
| US-4144230-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | claimed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | claimed |