SCHEMBL5609324

SCHEMBL5609324

CCCC[Al](CC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.38
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL967574 0.97 TSHR (0.38) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL3479674 0.93
SCHEMBL1668311 0.91 TSHR (0.33) TSHRLMNATHRB
SCHEMBL9506031 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL9350167 0.90 TSHR (0.38) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL6053749 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL9854440 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL6053526 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL15454 0.85 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL969291 0.83 TSHR (0.44) TSHRLMNATHRBALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423769-B Compounds in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2024-04-26 CN claimed
CN-116057082-B Ultra-high molecular weight polyethylene polymers with improved processability and morphology SABIC环球技术有限责任公司 2025-02-25 CN disclosed
CN-115066444-B Post metallocene compound SABIC环球技术有限责任公司 2024-06-11 CN disclosed
CN-117561284-A Ethylene-alpha-olefin copolymer and process for producing the same SABIC环球技术有限责任公司 2024-02-13 CN disclosed
CN-113286831-B Substituted bis 2-indenyl metallocene compounds SABIC环球技术有限责任公司 2023-05-09 CN disclosed
CN-116057082-A Ultra-high molecular weight polyethylene polymers with improved processability and morphology SABIC环球技术有限责任公司 2023-05-02 CN disclosed
US-7276463-B2 Polymerization catalyst for α-olefins and process for production of α-olefin polymers therewith JAPAN POLYPROPYLENE CORPORATION (JP) 2007-10-02 US disclosed
US-7122691-B2 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-17 US disclosed
US-20060068984-A1 Plymerization catalyst for a-olefins and process for production of alpha-olefin polymers therewith JAPAN POLYCHEM CORPORATION (JP) 2006-03-30 US disclosed
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-10-06 US disclosed
EP-1548035-A1 CATALYST FOR POLYMERIZING a-OLEFIN AND PRODUCTION METHOD OF a-OLEFIN POLYMER USING THE SAME Japan Polypropylene Corporation (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer CCNT1, C5, C9 TSHR 4243/4885LMNA 2592/4885THRB 3963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.