Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830352 | 0.98 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL27392992 | 0.98 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28087678 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31621131 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28877228 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9488008 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL3190479 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL6142430 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9651160 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Isobutane SCHEMBL23794926 | 0.90 | TSHR (0.78) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470175-B1 | OLIGOMERIC CHAIN EXTENDERS FOR PROCESSING, POST-PROCESSING AND RECYCLING OF CONDENSATION POLYMERS, SYNTHESIS, COMPOSITIONS AND APPLICATIONS | BASF CORP (US) | 2007-03-14 | — | — | EP | disclosed |