SCHEMBL5610445

SCHEMBL5610445

Cc1ccc2c(c1-c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C=C(C(C)(C)C)C2C[SiH2]CC1C(C(C)(C)C)=Cc2c1ccc(C)c2-c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.33
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609647 0.87 IKBKB (0.35) IKBKBRXRARXRBRXRG
SCHEMBL5610298 0.84 IKBKB (0.33) IKBKBRXRARXRBRXRG
SCHEMBL5609993 0.83 IKBKB (0.32) IKBKBRXRARXRBRXRG
SCHEMBL5608811 0.82 IKBKB (0.32) IKBKB
SCHEMBL5609318 0.81
SCHEMBL4627794 0.81 RXRB (0.31) RXRARXRB
SCHEMBL5609997 0.80 IKBKB (0.30) IKBKB
SCHEMBL5721568 0.78 POLB (0.30)
SCHEMBL5614615 0.75 IKBKB (0.32) IKBKB
SCHEMBL5610459 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-B1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEM PATENTS INC (US) 2007-07-25 EP disclosed