Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610494 | 1.00 | PREP (0.36) | PREPSLC22A12NR4A2TAAR1TLR9 | |
| SCHEMBL8320319 | 1.00 | PREP (0.36) | PREPSLC22A12NR4A2TAAR1TLR9 | |
| SCHEMBL13772633 | 0.91 | PREP (0.37) | PREPNR4A2TAAR1HCRTR1HCRTR2 | |
| SCHEMBL2994902 | 0.86 | NR4A2 (0.41) | NR4A2TAAR1KDM4EGAAMAPT | |
| SCHEMBL3004192 | 0.83 | SOS1 (0.37) | PREPSLC22A12HCRTR1HCRTR2KDM4E | |
| SCHEMBL4156704 | 0.83 | SOS1 (0.37) | PREPSLC22A12HCRTR1HCRTR2KDM4E | |
| SCHEMBL3000818 | 0.83 | SOS1 (0.37) | PREPSLC22A12HCRTR1HCRTR2KDM4E | |
| SCHEMBL5103670 | 0.81 | TDP1 (0.42) | HCRTR1HCRTR2KDM4ETDP1L3MBTL1 | |
| SCHEMBL8334752 | 0.81 | TDP1 (0.42) | HCRTR1HCRTR2KDM4ETDP1L3MBTL1 | |
| SCHEMBL5103666 | 0.81 | TDP1 (0.42) | HCRTR1HCRTR2KDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747016-A2 | USE OF DIPYRIDAMOLE FOR TREATMENT OF RESISTANCE TO PLATELET INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113006-A2 | USE OF DIPYRIDAMOLE FOR TREATMENT OF RESISTANCE TO PLATELET INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |