Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611334 | 1.00 | HCAR2 (0.44) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8085681 | 1.00 | HCAR2 (0.44) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL6061014 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9239993 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL6061013 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL16657264 | 0.91 | HCAR2 (0.56) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL4926884 | 0.89 | HCAR2 (0.57) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL4924867 | 0.89 | HCAR2 (0.57) | HCAR2ATMKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9004563 | 0.88 | GSTP1 (0.38) | HCAR2ATMALDH1A1TP53CYP3A4 | |
| SCHEMBL15794884 | 0.88 | HCAR2 (0.35) | HCAR2ATMALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186656-A | Anti-aging asphalt regenerant and preparation method and application thereof | 广州市市政工程维修处有限公司 | 2023-12-08 | — | — | CN | claimed |
| US-9562119-B2 | Ethylene polymerization catalysts | W. R. GRACE & CO.-CONN. (US) | 2017-02-07 | — | — | US | claimed |
| EP-2576633-A2 | ETHYLENE POLYMERIZATION CATALYSTS | BASF Corporation (US) | 2013-04-10 | — | — | EP | claimed |
| WO-2011149656-A2 | ETHYLENE POLYMERIZATION CATALYSTS | BASF CORPORATION (US) | 2011-12-01 | — | — | WO | claimed |
| US-20110294970-A1 | ETHYLENE POLYMERIZATION CATALYSTS | BASF CATALYSTS, LLC (US) | 2011-12-01 | — | — | US | claimed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | claimed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | claimed |
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | claimed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | claimed |
| CN-117186656-A | Anti-aging asphalt regenerant and preparation method and application thereof | 广州市市政工程维修处有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-2876118-B1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO LTD (JP) | 2022-04-06 | — | — | EP | disclosed |
| EP-3689918-A1 | CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND PROPYLENE- -OLEFIN COPOLYMER | Toho Titanium CO., LTD. (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-20200199274-A1 | CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN AND PROPYLENE-ALPHA-OLEFIN COPOLYMER | TOHO TITANIUM CO., LTD. (JP) | 2020-06-25 | — | — | US | disclosed |
| US-20200140577-A1 | CATALYST FOR POLYMERIZATION OF AN OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN AND PROPYLENE-alpha-OLEFIN COPOLYMER | TOHO TITANIUM CO., LTD. (JP) | 2020-05-07 | — | — | US | disclosed |
| EP-1533322-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | Toho Catalyst Co., Ltd. (JP) | 2005-05-25 | — | — | EP | disclosed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5346978-A | Polymeric compositions useful in oxygen permeable contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294970-A1 | ETHYLENE POLYMERIZATION CATALYSTS | ESR1, MSMO1, MCM5 | HCAR2 3524/4885ATM 44/4885KEAP1 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.