Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611982 | 1.00 | TSHR (0.50) | TSHRALDH1A1HPGDPRKCANPSR1 | |
| SCHEMBL10786020 | 0.85 | TSHR (0.46) | TSHRALDH1A1HPGDPRKCATDP1 | |
| SCHEMBL5612299 | 0.85 | TSHR (0.36) | TSHRPRKCA | |
| SCHEMBL29794852 | 0.82 | TSHR (0.47) | TSHRALDH1A1HPGDPRKCANPSR1 | |
| SCHEMBL5611935 | 0.81 | NPSR1 (0.55) | TSHRALDH1A1PRKCANPSR1TDP1 | |
| SCHEMBL5611944 | 0.81 | NPSR1 (0.55) | TSHRALDH1A1PRKCANPSR1TDP1 | |
| SCHEMBL6135791 | 0.80 | TSHR (0.44) | TSHRALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL6135787 | 0.80 | TSHR (0.44) | TSHRALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL29220345 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDPRKCANPSR1 | |
| SCHEMBL5612059 | 0.78 | TSHR (0.43) | TSHRALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425317-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2007-12-19 | — | — | EP | disclosed |
| US-7015170-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2006-03-21 | — | — | US | disclosed |
| EP-1425317-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.p.A. (IT) | 2004-06-09 | — | — | EP | disclosed |
| US-20040014595-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-01-22 | — | — | US | disclosed |
| WO-2003022894-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-03-20 | — | — | WO | disclosed |