SCHEMBL561237

SCHEMBL561237

CCCCCCCCCCCCCCCCCCC(CON(Cc1ccccc1)Cc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.44
PTGES O14684 2/20 0.44
ALOX5 P09917 2/20 0.44
PPARG P37231 2/20 0.44
CNR2 P34972 1/20 0.43
MMP2 P08253 9/20 0.42
MMP1 P03956 4/20 0.42
MMP3 P08254 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2238584 0.83 CYP1A2 (0.49) PPARG
SCHEMBL562327 0.80 GRIK1 (0.50)
SCHEMBL133566 0.78 SLC1A1 (0.57) PTGESALOX5PPARGCNR2
SCHEMBL133567 0.78 SLC1A1 (0.57) PTGESALOX5PPARGCNR2
SCHEMBL7086877 0.77 CYP1A2 (0.42) ALOX5PPARGMMP1MMP3
SCHEMBL9655121 0.77 FOLH1 (0.66) CSNK1EPTGESALOX5PPARGMMP2
SCHEMBL9653477 0.77 FOLH1 (0.66) CSNK1EPTGESALOX5PPARGMMP2
SCHEMBL10955140 0.77 FOLH1 (0.66) CSNK1EPTGESALOX5PPARGMMP2
SCHEMBL9653480 0.77 FOLH1 (0.66) CSNK1EPTGESALOX5PPARGMMP2
SCHEMBL3242850 0.77 FOLH1 (0.66) CSNK1EPTGESALOX5PPARGMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240462-B1 SUBSTITUTED AMINOOXYPROPANOATE CIBA-GEIGY AG (CH) 1990-08-01 EP claimed
EP-0240462-A2 Substituted aminooxypropanoate CIBA-GEIGY AG (CH) 1987-10-07 EP claimed
EP-2880092-B1 PHOSPHITE COMPOSITIONS SI GROUP SWITZERLAND CHAA GMBH (CH) 2020-09-30 EP disclosed
EP-2459576-B1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER ADDIVANT SWITZERLAND GMBH (CH) 2018-11-21 EP disclosed
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP disclosed
EP-2917276-B1 STABILIZED HIGH-DENSITY POLYETHYLENE COMPOSITION WITH IMPROVED RESISTANCE TO DETERIORATION AND STABILZER SYSTEM EQUISTAR CHEM LP (US) 2018-07-18 EP disclosed
EP-2459574-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2018-06-20 EP disclosed
EP-1885787-B1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM CO (US) 2018-01-10 EP disclosed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP disclosed
EP-2917276-A1 STABILIZED HIGH-DENSITY POLYETHYLENE COMPOSITION WITH IMPROVED RESISTANCE TO DETERIORATION AND STABILZER SYSTEM Equistar Chemicals LP (US) 2015-09-16 EP disclosed
EP-2459578-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2015-08-19 EP disclosed
US-5141975-A Melt processability, discoloration inhibition GENERAL ELECTRIC COMPANY (US) 1992-08-25 US disclosed
US-5137950-A Reacting phosphorous trichloride with alcohol; polymer stabilizer BORG-WARNER SPECIALTY CHEMICALS, INC. (US) 1992-08-11 US disclosed
US-5124472-A From tetrahydroabiethyl alcohol GENERAL ELECTRIC COMPANY (US) 1992-06-23 US disclosed
EP-0460461-A1 Hydrolytically stable phosphites GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5023285-A Melt flow and color stabilizers for polymers G E SPECIALTY CHEMICALS (US) 1991-06-11 US disclosed
EP-0240462-B1 SUBSTITUTED AMINOOXYPROPANOATE CIBA-GEIGY AG (CH) 1990-08-01 EP disclosed
EP-0356687-A1 Bis (tri-tertiary-alkylphenoxy) diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
EP-0356688-A2 3, 9-diphosphaspiroundecanes and process for making 3, 9-diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
EP-0240462-A2 Substituted aminooxypropanoate CIBA-GEIGY AG (CH) 1987-10-07 EP disclosed