Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | CNR2 | P34972 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310665 | 0.90 | CNR1 (0.74) | CNR1KCNH2CNR2 | |
| SCHEMBL3311149 | 0.87 | CNR1 (0.70) | CNR1KCNH2CNR2 | |
| SCHEMBL3313844 | 0.87 | CNR1 (0.70) | CNR1KCNH2CNR2 | |
| SCHEMBL3312679 | 0.85 | CNR1 (1.00) | CNR1KCNH2CNR2 | |
| SCHEMBL3312773 | 0.84 | CNR1 (0.80) | CNR1KCNH2CNR2 | |
| SCHEMBL3312035 | 0.83 | CNR1 (1.00) | CNR1KCNH2CNR2 | |
| SCHEMBL3310443 | 0.83 | CNR1 (0.87) | CNR1KCNH2CNR2 | |
| SCHEMBL13329555 | 0.83 | CNR1 (0.74) | CNR1KCNH2CNR2 | |
| SCHEMBL3310303 | 0.82 | CNR1 (1.00) | CNR1KCNH2CNR2 | |
| SCHEMBL3305796 | 0.82 | CNR1 (0.87) | CNR1KCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863810-A1 | NOVEL TETRAHYDRO-1H-PYRIDO [4,3-b] INDOLE DERIVATIVES AS CB1' RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006101434-A1 | NOVEL TETRAHYDRO-1H-PYRIDO [4,3-b] INDOLE DERIVATIVES AS CB1’ RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2006-09-28 | — | — | WO | disclosed |