SCHEMBL5615464

SCHEMBL5615464

C[C](OC(=O)CC(C)=O)OC(=O)CC(C)=O

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.60
GAA P10253 2/20 0.60
SI P14410 2/20 0.60
MGAM2 Q2M2H8 2/20 0.60
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 4/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 2/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
HSD17B10 Q99714 1/20 0.33
TRPA1 O75762 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449524 0.88 MGAM (0.67) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8364199 0.82 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL586203 0.82 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL15847228 0.82 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28224529 0.82 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL9280063 0.82 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL25283117 0.80 MGAM (0.57) MGAMGAASIMGAM2ALDH1A1
SCHEMBL22472179 0.80 MGAM (0.57) MGAMGAASIMGAM2ALDH1A1
SCHEMBL17994176 0.80 MGAM (0.57) MGAMGAASIMGAM2ALDH1A1
SCHEMBL2532133 0.80 MGAM (0.57) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007056262-A2 POLYMER COMPOSITIONS HAVING NOVEL CURE SYSTEMS AND METHOD OF MAKING ARTICLES WITH SAME DOW REICHHOLD SPECIALTY LATEX, LLC (US) 2007-05-18 WO disclosed
EP-1355964-B1 POLYMERS HAVING CURE SYSTEM REICHHOLD INC (US) 2005-03-30 EP disclosed
US-6624274-B1 Curable conjugated diene copolymer with chelating monomer; sulfur-free DOW REICHHOLD SPECIALTY LATEX LLC 2003-09-23 US disclosed