SCHEMBL5615501

SCHEMBL5615501

CCCCCC[Si]1(CCCCCC)CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016691 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL8651059 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL29176065 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL5615194 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL20240976 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL5615511 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL5615296 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL5615453 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL5615428 1.00 TSHR (0.32) TSHRTHRBEPHX1
SCHEMBL29187440 1.00 TSHR (0.32) TSHRTHRBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018104079-A1 PIPE PRODUCED WITH A POLYMER COMPOSITION COMPRISING A POLYOLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-14 WO claimed
WO-1998041397-A1 AN ANTIWETTING COMPOSITION FOR FABRICS AND FIBROUS SUBSTRATES POROUS MEDIA CORPORATION (US) 1998-09-24 WO claimed
US-5792711-A CURABLE DISPERSIO CONTAINING POLYMERIC FLUOROALIPHATIC ESTER AND SILICONE RESIN IN WATER-BASED CARRIER POROUS MEDIA CORPORATION (US) 1998-08-11 US claimed
WO-2018104079-A1 PIPE PRODUCED WITH A POLYMER COMPOSITION COMPRISING A POLYOLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-14 WO disclosed
EP-1179566-B1 ELASTOMER COMPOSITION AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME KANEKA CORP (JP) 2007-03-07 EP disclosed
CN-1780637-A Liquid, aqueous, pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTHCARE AG (CH) 2006-05-31 CN disclosed
US-6534594-B1 Methacrylate-siloxane block copolymer; impact strength KANEKA CORPORATION (JP) 2003-03-18 US disclosed
EP-1179566-A1 ELASTOMER COMPOSITION AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2002-02-13 EP disclosed
WO-1998041397-A1 AN ANTIWETTING COMPOSITION FOR FABRICS AND FIBROUS SUBSTRATES POROUS MEDIA CORPORATION (US) 1998-09-24 WO disclosed
US-5792711-A CURABLE DISPERSIO CONTAINING POLYMERIC FLUOROALIPHATIC ESTER AND SILICONE RESIN IN WATER-BASED CARRIER POROUS MEDIA CORPORATION (US) 1998-08-11 US disclosed
US-4477524-A BLEND OF LUBRICANT, CURABLE SILICON, AND AMIDE PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4394414-A Aqueous sizing composition for glass fibers for use on chopped glass fibers PPG INDUSTRIES, INC. (US) 1983-07-19 US disclosed
US-4210697-A Process for preparing hydrophobic porous fibrous sheet material of high strength and porosity and product PALL CORPORATION (US) 1980-07-01 US disclosed