Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664523 | 0.80 | MEN1 (0.30) | NPC1RAB9A | |
| SCHEMBL4667550 | 0.80 | NPC1 (0.32) | NPC1RAB9AALDH1A1 | |
| SCHEMBL769081 | 0.80 | NPC1 (0.38) | NPC1RAB9AALDH1A1 | |
| SCHEMBL673359 | 0.80 | CNR1 (0.40) | NPC1RAB9A | |
| SCHEMBL4664043 | 0.79 | XPO1 (0.33) | — | |
| SCHEMBL4664025 | 0.79 | NPC1 (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22289027 | 0.79 | CNR1 (0.42) | NPC1RAB9A | |
| SCHEMBL226073 | 0.79 | TSHR (0.35) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL345788 | 0.76 | NPC1 (0.33) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL224924 | 0.76 | CNR1 (0.38) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050394-A2 | POLYMERIC RADIATION-ABSORBING MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20070092830-A1 | Polymeric radiation-absorbing materials and ophthalmic devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-04-26 | — | — | US | disclosed |