Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105110 | 0.87 | P2RY12 (0.72) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4112645 | 0.81 | P2RY12 (0.77) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4097532 | 0.81 | P2RY12 (0.60) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4508755 | 0.80 | P2RY12 (0.54) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4106096 | 0.77 | P2RY12 (0.61) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4097996 | 0.77 | P2RY12 (0.58) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4109942 | 0.75 | P2RY12 (0.81) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5343437 | 0.75 | P2RY12 (0.79) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4110504 | 0.75 | P2RY12 (0.66) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4103570 | 0.75 | P2RY12 (0.58) | P2RY12CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | claimed |