Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616270 | 0.92 | MAPT (0.62) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL14640845 | 0.82 | MAPT (0.84) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL14640576 | 0.81 | MAPT (0.81) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL14640779 | 0.81 | MAPT (0.63) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL10972822 | 0.80 | NPSR1 (0.65) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL10974451 | 0.79 | NPSR1 (0.64) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL14640561 | 0.79 | MAPT (1.00) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL22573447 | 0.78 | HSD17B10 (0.64) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL5616341 | 0.78 | MAPT (0.68) | MAPTNPSR1ALDH1A1CYP1A2GAA | |
| SCHEMBL5616320 | 0.78 | MAPT (1.00) | MAPTNPSR1ALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011721-A1 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007011721-A1 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |