Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | CETP | P11597 | 4/20 | 0.65 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.65 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GMNN | O75496 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.65 |
| ▸ | CCR6 | P51684 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | UBE2N | P61088 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705510 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL9112746 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL28772557 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL4608213 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL312332 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL27491463 | 1.00 | MEN1 (0.65) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL9011612 | 0.98 | MEN1 (0.63) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL9513991 | 0.94 | S1PR1 (0.59) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL8531537 | 0.94 | S1PR1 (0.59) | MEN1KMT2ACETPSPHK2SPHK1 | |
| SCHEMBL13009766 | 0.89 | SPHK2 (0.67) | MEN1KMT2ACETPSPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136635-A1 | ENHANCEMENT OF RADIATION THERAPY AND/OR CHEMOTHERAPY WITH ACID CERAMIDASE MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2007-11-29 | — | — | WO | disclosed |