Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 11/20 | 0.65 |
| ▸ | AURKA | O14965 | 12/20 | 0.62 |
| ▸ | KDR | P35968 | 6/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538910 | 1.00 | AURKB (0.65) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5616526 | 0.90 | AURKB (0.62) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5594005 | 0.90 | AURKB (0.62) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5594000 | 0.90 | AURKB (0.62) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5616527 | 0.90 | AURKB (0.62) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL14539062 | 0.89 | AURKB (0.61) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5594088 | 0.89 | AURKA (0.66) | AURKBAURKAKDRCHEK1KIT | |
| SCHEMBL5604292 | 0.88 | AURKA (0.65) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5593785 | 0.88 | AURKA (0.65) | AURKBAURKAKDRCHEK1KIT | |
| SCHEMBL5604288 | 0.88 | AURKA (0.65) | AURKBAURKAKDRFGFR1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |