Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627557 | 0.81 | CYP2A6 (0.41) | TSHRSMN1; SMN2MAPK1LMNAGAA | |
| SCHEMBL11719202 | 0.79 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL10680762 | 0.79 | CYP1A2 (0.47) | TSHRSLC6A4SLC6A3SMN1; SMN2MAPK1 | |
| SCHEMBL10300805 | 0.78 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL26985761 | 0.78 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL1664714 | 0.74 | TSHR (0.47) | TSHRSLC6A3SLC6A2SMN1; SMN2MAPK1 | |
| SCHEMBL18288021 | 0.74 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL18288019 | 0.73 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11472421 | 0.73 | SLC6A4 (0.43) | TSHRSLC6A4SLC6A3SLC6A2SMN1; SMN2 | |
| SCHEMBL5167951 | 0.72 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057658-A1 | PALLADIUM CATALYSED HECK ARYLATION OR VINYLATION OF 1-SUBSTITUTED OLEFINS | THE UNIVERSITY OF LIVERPOOL (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057658-A1 | PALLADIUM CATALYSED HECK ARYLATION OR VINYLATION OF 1-SUBSTITUTED OLEFINS | THE UNIVERSITY OF LIVERPOOL (GB) | 2007-05-24 | — | — | WO | disclosed |