⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264914 | 0.65 | PNP (0.38) | — | |
| SCHEMBL260110 | 0.65 | PNP (0.38) | — | |
| SCHEMBL14510491 | 0.64 | — | — | |
| SCHEMBL15740158 | 0.64 | PNP (0.37) | — | |
| SCHEMBL3888596 | 0.61 | ADORA2A (0.36) | — | |
| SCHEMBL3895909 | 0.59 | PNP (0.61) | — | |
| SCHEMBL3888177 | 0.58 | PNP (0.38) | — | |
| SCHEMBL9912296 | 0.57 | FUCA1 (0.41) | — | |
| SCHEMBL31484433 | 0.57 | DRD1 (0.34) | — | |
| SCHEMBL15740315 | 0.56 | PNP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814561-A2 | THERAPEUTIC FUROPYRIMIDINES AND THIENOPYRIMIDINES | Biocryst Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006050161-A2 | THERAPEUTIC FUROPYRIMIDINES AND THIENOPYRIMIDINES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-05-11 | — | — | WO | claimed |