⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738533 | 0.78 | — | — | |
| SCHEMBL14359833 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL16486264 | 0.74 | AKR1B1 (0.40) | — | |
| SCHEMBL404116 | 0.74 | AKR1B1 (0.40) | — | |
| SCHEMBL7625680 | 0.73 | AKR1B1 (0.43) | — | |
| SCHEMBL270568 | 0.73 | — | — | |
| SCHEMBL28205833 | 0.73 | — | — | |
| SCHEMBL14211014 | 0.73 | — | — | |
| SCHEMBL14360192 | 0.72 | AKR1B1 (0.32) | — | |
| SCHEMBL8939159 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309746-B2 | Polymers containing silane | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2007-12-18 | — | — | US | disclosed |
| EP-1549682-B1 | POLYMERS CONTAINING SILANE | WACKER POLYMER SYSTEMS GMBH (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-20050182223-A1 | Polymers containing silane | WACKER CHEMIE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| EP-1549682-A1 | POLYMERS CONTAINING SILANE | Wacker Polymer Systems GmbH & Co. KG (DE) | 2005-07-06 | — | — | EP | disclosed |
| US-20040266855-A1 | 3-(4,5,6,7-tetrahydroindol-2-ylmethylidiene)-2-indolinone derivatives as kinase inhibitors | SUGEN, INC. | 2004-12-30 | — | — | US | disclosed |
| US-6777417-B2 | ANTICANCER AGENTS | SUGEN, INC. | 2004-08-17 | — | — | US | disclosed |
| EP-1436259-A1 | 3-(4,5,6,7-TETRAHYDROINDOL-2-YLMETHYLIDIENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS | Liang, Congxin (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2004013187-A1 | POLYMERS CONTAINING SILANE | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2004-02-12 | — | — | WO | disclosed |
| US-20030119819-A1 | 3-(4,5,6,7-Tetrahydroindol-2-ylmethylidiene-2-indolinone derivatives as kinase inhibitors | SUGEN, INC. | 2003-06-26 | — | — | US | disclosed |
| WO-2003022815-A1 | 3-(4,5,6,7-TETRAHYDROINDOL-2-YLMETHYLIDIENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS | SUGEN, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
| US-4060677-A | Process for molecular weight lowering of vinyl halide polymers employing saturated carbon to carbon bonded aldehydes | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4046883-A | Fungicidal compositions based on polyimides of phosphorus and method of treating plants therewith | PHILAGRO S.A. (FR) | 1977-09-06 | — | — | US | disclosed |