⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120245 | 1.00 | — | — | |
| Diethanolamine SCHEMBL11585335 | 0.81 | TDP1 (0.32) | — | |
| SCHEMBL220417 | 0.72 | — | — | |
| SCHEMBL10771052 | 0.72 | — | — | |
| SCHEMBL6645226 | 0.71 | TSHR (0.36) | — | |
| SCHEMBL8887908 | 0.71 | CYP1A2 (0.42) | — | |
| Propylene Glycol SCHEMBL29020315 | 0.69 | TDP1 (0.71) | — | |
| SCHEMBL4429855 | 0.69 | — | — | |
| SCHEMBL9230623 | 0.69 | — | — | |
| SCHEMBL443754 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011218-A1 | POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF | BROWN UNIVERSITY (US) | 2024-01-11 | — | — | WO | disclosed |
| US-11759458-B2 | Indane-amines as PD-L1 antagonists | CHEMOCENTRYX, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3564233-B1 | 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS | NOVARTIS AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| EP-4101849-A1 | 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS | Novartis AG (CH) | 2022-12-14 | — | — | EP | disclosed |
| US-20220387428-A1 | 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS | NOVARTIS AG (CH) | 2022-12-08 | — | — | US | disclosed |
| US-20220175746-A1 | INDANE-AMINES AS PD-L1 ANTAGONISTS | CHEMOCENTRYX, INC. | 2022-06-09 | — | — | US | disclosed |
| CN-114531850-A | Pharmaceutical composition and kit characterized by containing novel penicillin derivative or salt thereof and 1 or more compounds selected from beta-lactamase inhibitory compound and antibacterial compound or salt thereof | 富士胶片株式会社 | 2022-05-24 | — | — | CN | disclosed |
| CN-114316102-A | Alkoxy magnesium carrier, polyethylene catalyst and preparation method thereof | 北京吉海川科技发展有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11229648-B2 | 1,4-disubstituted pyridazine analogs thereof and methods for treating SMN-deficiency-related conditions | NOVARTIS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| EP-2885288-B1 | 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS | NOVARTIS AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| US-4271262-A | Photoimaging process which uses sulfide containing polymeric films | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4266004-A | Photoimageable material of polymeric material having organic sulfide and photo-oxidation sensitizer | MONSANTO COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0020401-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 1,4-DIAZA-2-CYCLOALKANONE AND SUBSTITUTED DERIVATIVES THEREOF. | GOODRICH CO B F (US) | 1981-01-07 | — | — | EP | disclosed |
| EP-0020401-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF 1,4-DIAZA-2-CYCLOALKANONE AND SUBSTITUTED DERIVATIVES THEREOF. | GOODRICH CO B F (US) | 1980-08-11 | — | — | EP | disclosed |
| WO-1980000702-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 1,4-DIAZA-2-CYCLOALKANONE AND SUBSTITUTED DERIVATIVES THEREOF | GOODRICH CO B F (US) | 1980-04-17 | — | — | WO | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |
| EP-0004460-A1 | Improved synthesis of 1,4-diaza-2-cycloalkanone and substituted derivatives thereof | The B.F. GOODRICH Company (US) | 1979-10-03 | — | — | EP | disclosed |
| US-4110379-A | FIRE RETARDANT | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 1978-08-29 | — | — | US | disclosed |
| US-4069173-A | POLYCARBOXYLIC ACID | ARMSTRONG CORK COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-4045440-A | ETHERIFICATION WITH METHYL IODIDE, OXIDATION WITH MANGANESE DIOXIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-08-30 | — | — | US | disclosed |