Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619081 | 1.00 | MAOB (0.56) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL5619511 | 0.94 | BCHE (0.48) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL5619504 | 0.94 | BCHE (0.48) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL5620399 | 0.87 | CYP1B1 (0.53) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL25210277 | 0.87 | MAPT (0.58) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL25210278 | 0.87 | MAPT (0.58) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL25219890 | 0.87 | MAPT (0.58) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL5620395 | 0.87 | CYP1B1 (0.53) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL9177615 | 0.87 | PDE4B (0.46) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL31233307 | 0.87 | MAOB (0.53) | MAOBMAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276523-B2 | Aminopyridine derivatives as estrogen receptor modulators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-02 | — | — | US | disclosed |
| US-20040152688-A1 | Aminopyridine derivatives as estrogen receptor modulators | SMITHKLINE BEECHAM CORPORATION | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152688-A1 | Aminopyridine derivatives as estrogen receptor modulators | ESR2, GPER1, ESR1 | MAOB 1367/4885MAPT 2628/4885LMNA 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.