⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391076 | 1.00 | — | — | |
| SCHEMBL3712628 | 0.79 | — | — | |
| SCHEMBL30901327 | 0.79 | — | — | |
| SCHEMBL858342 | 0.79 | — | — | |
| SCHEMBL5132399 | 0.77 | — | — | |
| SCHEMBL23304154 | 0.75 | — | — | |
| SCHEMBL18333004 | 0.75 | — | — | |
| SCHEMBL20844100 | 0.75 | — | — | |
| SCHEMBL20844096 | 0.75 | — | — | |
| SCHEMBL311281 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2290 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | claimed |
| CN-117209485-A | Pyrimidine skeleton compound with anti-tumor activity and preparation method and application thereof | 四川大学华西医院 | 2023-12-12 | — | — | CN | claimed |
| CN-115141181-A | Novel small molecule compound and preparation method and application thereof | 温州医科大学 | 2022-10-04 | — | — | CN | claimed |
| CN-113512004-B | Synthetic method of 2-fluoro-5-trifluoromethylpyrimidine | 金凯(辽宁)生命科技股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113754591-A | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2021-12-07 | — | — | CN | claimed |
| CN-113512004-A | Synthetic method of 2-fluoro-5-trifluoromethylpyrimidine | 金凯(辽宁)生命科技股份有限公司 | 2021-10-19 | — | — | CN | claimed |
| EP-0579020-B1 | Process for the preparation of 5-(Trifluoromethyl) uracil and as new compounds 2,4-dichloro-5-trichloromethyl pyrimidine and 2,4-dufluoro-5-trifluoromethyl-pyrimidine | BAYER AG (DE) | 1998-01-21 | — | — | EP | claimed |
| US-5352787-A | Process for the preparation of 5-(trifluoromethyl)-uracil, and the novel compounds 2,4-dichloro-5-trichloromethyl-pyrimidine and 2,4-difluoro-5-trifluoromethyl-pyrimidine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-04 | — | — | US | claimed |
| EP-0579020-A1 | Process for the preparation of 5-(Trifluoromethyl) uracil and as new compounds 2,4-dichloro-5-trichloromethyl pyrimidine and 2,4-dufluoro-5-trifluoromethyl-pyrimidine | BAYER AG (DE) | 1994-01-19 | — | — | EP | claimed |
| EP-0283375-B1 | PROCESS FOR THE PREPARATION OF POLYCHLOROPHOSPHAZENE | ELF ATOCHEM S.A. (FR) | 1991-10-30 | — | — | EP | claimed |
| US-4810480-A | Preparation of polychlorophosphazene | ATOCHEM (FR) | 1989-03-07 | — | — | US | claimed |
| JP-6073023-A | — | — | None | — | — | JP | disclosed |
| US-20260146124-A1 | RESIN COMPOSITION AND USES OF THE SAME | TAIWAN UNION TECHNOLOGY CORPORATION (TW) | 2026-05-28 | — | — | US | disclosed |
| US-20260146047-A1 | MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-05-28 | — | — | US | disclosed |
| EP-4745138-A1 | THIO-GLUTARIMIDO ISOINDOLINONE DERIVATIVE, BIFUNCTIONAL PROTEIN DEGRADER CONTAINING SAME, AND USES THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| EP-0579020-A1 | Process for the preparation of 5-(Trifluoromethyl) uracil and as new compounds 2,4-dichloro-5-trichloromethyl pyrimidine and 2,4-dufluoro-5-trifluoromethyl-pyrimidine | BAYER AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0579020-A1 | Process for the preparation of 5-(Trifluoromethyl) uracil and as new compounds 2,4-dichloro-5-trichloromethyl pyrimidine and 2,4-dufluoro-5-trifluoromethyl-pyrimidine | BAYER AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |
| US-4810480-A | Preparation of polychlorophosphazene | ATOCHEM (FR) | 1989-03-07 | — | — | US | disclosed |
| EP-0014390-A1 | 2-Amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido (2,3-d) pyrimidine-6-carboxylic acids, pharmaceutical compositions containing them and processes for their preparation | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |