SCHEMBL5619941

SCHEMBL5619941

N#Cc1c(CNS(=O)(=O)c2cccc(F)c2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1.N#Cc1c(CNS(=O)(=O)c2ccccc2F)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL907994 0.94 CNR1 (0.44) CNR1
SCHEMBL909118 0.92 CNR1 (0.47) CNR1
SCHEMBL5622086 0.84 SLC22A12 (0.44) CNR1
SCHEMBL909395 0.81 CNR1 (0.49) CNR1
SCHEMBL908716 0.79 SLC22A12 (0.47) CNR1
SCHEMBL2769028 0.79 OPRL1 (0.48) CNR1
SCHEMBL908264 0.79 CNR1 (0.47) CNR1
SCHEMBL5620329 0.77 CNR1 (0.43) CNR1
SCHEMBL1377828 0.77 OPRL1 (0.46) CNR1
SCHEMBL908989 0.76 CNR1 (0.51) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297710-B1 Derivatives of N-[(1,5-diphenyl-1H-pyrazol-3-yl)methyl]sulfonamide, their preparation and their application in therapeutics SANOFI-AVENTIS (FR) 2007-11-20 US claimed