2,6-Dichloroisonicotinic Acid

2,6-Dichloroisonicotinic Acid

SCHEMBL56204

O=C(O)c1cc(Cl)nc(Cl)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.56
TSHR P16473 3/20 0.54
ALOX15 P16050 2/20 0.54
HIF1A Q16665 1/20 0.54
TTR P02766 1/20 0.52
S1PR2 O95136 1/20 0.48
HCAR1 Q9BXC0 1/20 0.48
HCAR2 Q8TDS4 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CTRC Q99895 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dichloroisonicotinic Acid SCHEMBL27673665 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL27653662 0.97 TSHR (0.58) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL27653711 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL7828838 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL2264628 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL27673705 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL11071500 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL27653766 0.97 TPMT (0.54) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL28513386 0.91 TPMT (0.48) TPMTTSHRALOX15HIF1ATTR
2,6-Dichloroisonicotinic Acid SCHEMBL11350560 0.87 TPMT (0.45) TPMTTSHRALOX15HIF1ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US claimed
CN-119751346-A Vinyl pyridine prodrug compound and preparation method and application thereof 中国药科大学 2025-04-04 CN claimed
CN-119452806-A Cultivation method of high stress resistance black glutinous rice 湖南省农业装备研究所 2025-02-18 CN claimed
CN-119422728-A Annual tea garden management method for effectively preventing and controlling occurrence of tea cake diseases 广东省农业科学院茶叶研究所 2025-02-14 CN claimed
US-20240268388-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-08-15 US claimed
US-20240260575-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-08-08 US claimed
CN-115322146-B Preparation method of 4-amino-2, 6-dichloropyridine 安徽峆一药业股份有限公司 2024-04-19 CN claimed
EP-4344545-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-04-03 EP claimed
EP-4338593-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-03-20 EP claimed
CN-117546870-A Inducer composition and method for improving total polysaccharide, total flavone and anoectochilus formosanus glycoside of anoectochilus formosanus effective components 广东省农业科学院作物研究所 2024-02-13 CN claimed
WO-1996036693-A9 MANIPULATION OF PLANT CELL AND TISSUE CULTURES 1997-01-23 WO claimed
WO-1996036693-A1 MANIPULATION OF PLANT CELL AND TISSUE CULTURES PHYTERA, INC. (US) 1996-11-21 WO claimed
WO-1996031513-A1 NOVEL INTERMEDIATES AND PROCESS FOR THE MANUFACTURE OF CAMPTOTHECIN DERIVATIVES (CPT-11) AND RELATED COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1996-10-10 WO claimed
EP-0334813-B1 Agents for the protection of plants against diseases CIBA GEIGY AG (CH) 1994-02-02 EP claimed
EP-0268775-B1 METHOD FOR PROTECTING PLANTS AGAINST DISEASES CIBA-GEIGY AG (CH) 1992-12-23 EP claimed
US-5095021-A PHENYLALKYLAMINES AND FUNGICIDES CONTAINING THESE BASF AKTIENGESELLSCHAFT (DE) 1992-03-10 US claimed
US-4968344-A FUNGICIDES, BACTERICIDES CIBA-GEIGY CORPORATION (US) 1990-11-06 US claimed
EP-0332104-A2 Chemically regulatable DNA sequences and genes and uses thereof CIBA-GEIGY AG (CH) 1989-09-13 EP claimed
EP-0268775-A1 Method for protecting plants against diseases CIBA-GEIGY AG (CH) 1988-06-01 EP claimed
CN-87106598-A Protective plant is avoided the method for disease 1988-05-04 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240268388-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION CYP51A1, HAAO, MGAM TPMT 972/4885TSHR 4347/4885ALOX15 1008/4885
US-20240260575-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION CYP51A1, PIK3C3, AADAC TPMT 3209/4885TSHR 3987/4885ALOX15 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.