Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.80 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249933 | 0.90 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8242311 | 0.89 | HDAC1 (1.00) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1402792 | 0.87 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1402794 | 0.87 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403480 | 0.85 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403477 | 0.85 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403262 | 0.83 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403260 | 0.83 | HDAC1 (0.80) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403355 | 0.82 | HDAC1 (0.79) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL1403357 | 0.82 | HDAC1 (0.79) | HDAC1HDAC4HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183298-B2 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2007-02-27 | — | — | US | disclosed |
| US-20050085515-A1 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors | TOPO TARGET UK LIMITED, (GB) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085515-A1 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885HDAC4 8/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.