Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63377 | 0.74 | METAP1 (0.43) | ADORA2AADORA1F2RL1ADRA1DADRA1A | |
| SCHEMBL8603493 | 0.65 | F2RL1 (0.48) | ADORA2AADORA1F2RL1ADRA1DADRA1A | |
| SCHEMBL7451095 | 0.64 | SMPD3 (0.40) | ADORA2AADORA1PDPK1 | |
| SCHEMBL81650 | 0.59 | NISCH (0.59) | MEN1ALDH1A1KMT2AMTORADK | |
| SCHEMBL102331 | 0.59 | PDPK1 (0.59) | ADORA2AADORA1ALDH1A1PDPK1METAP1 | |
| SCHEMBL28361849 | 0.57 | PDPK1 (0.40) | ADORA2AADORA1PDPK1METAP1 | |
| SCHEMBL14690672 | 0.57 | PDPK1 (0.39) | ADORA2AADORA1ALDH1A1PDPK1METAP1 | |
| SCHEMBL11655 | 0.57 | NISCH (0.48) | MEN1ALDH1A1KMT2AMTORADK | |
| SCHEMBL5524325 | 0.57 | NISCH (0.39) | MEN1ALDH1A1KMT2AMTORADK | |
| Hydrochloric Acid SCHEMBL1536214 | 0.57 | NISCH (0.56) | MEN1ALDH1A1KMT2AMTORADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |