Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623491 | 0.92 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5623812 | 0.90 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5625845 | 0.87 | MAP2K1 (0.81) | MAP2K1MAP2K2 | |
| SCHEMBL5622823 | 0.84 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5623772 | 0.84 | MAP2K1 (0.74) | MAP2K1MAP2K2 | |
| SCHEMBL4234407 | 0.82 | MAP2K2 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5622740 | 0.82 | MAP2K1 (0.75) | MAP2K1MAP2K2 | |
| SCHEMBL1488587 | 0.81 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL29413425 | 0.81 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5622771 | 0.81 | MAP2K1 (0.81) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273877-B2 | 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY, LLC (US) | 2007-09-25 | — | — | US | claimed |
| US-20050026964-A1 | 5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY LLC | 2005-02-03 | — | — | US | claimed |
| US-7273877-B2 | 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY, LLC (US) | 2007-09-25 | — | — | US | disclosed |
| US-7273877-B2 | 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY, LLC (US) | 2007-09-25 | — | — | US | disclosed |
| US-7273877-B2 | 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY, LLC (US) | 2007-09-25 | — | — | US | disclosed |
| US-20050026964-A1 | 5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | WARNER-LAMBERT COMPANY LLC | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026964-A1 | 5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives | CYP3A5, CYP4B1, CYP3A4 | MAP2K1 4286/4885MAP2K2 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.