⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712421 | 0.73 | — | — | |
| SCHEMBL2589141 | 0.71 | — | — | |
| SCHEMBL4013797 | 0.69 | — | — | |
| SCHEMBL943850 | 0.67 | — | — | |
| SCHEMBL862150 | 0.67 | — | — | |
| SCHEMBL11938216 | 0.65 | — | — | |
| SCHEMBL14619109 | 0.65 | — | — | |
| SCHEMBL5704819 | 0.65 | — | — | |
| SCHEMBL874724 | 0.65 | — | — | |
| SCHEMBL19630871 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782407-B2 | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-10-10 | — | — | US | disclosed |
| US-9765030-B2 | Benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-09-19 | — | — | US | disclosed |
| EP-1848430-B1 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2017-08-02 | — | — | EP | disclosed |
| US-20170071930-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2017-03-16 | — | — | US | disclosed |
| US-20160000799-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2016-01-07 | — | — | US | disclosed |
| EP-2919765-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | Dr. Reddy's Laboratories Ltd. (IN) | 2015-09-23 | — | — | EP | disclosed |
| US-20150216866-A1 | SUBSTITUTED BENZYLAMINO QUINOLINES AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-08-06 | — | — | US | disclosed |
| US-9040558-B2 | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-05-26 | — | — | US | disclosed |
| WO-2014128564-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014076568-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-05-22 | — | — | WO | disclosed |
| US-20140134235-A1 | NOVEL BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-05-15 | — | — | US | disclosed |
| US-8604055-B2 | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2013-12-10 | — | — | US | disclosed |
| EP-1848430-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20070015758-A1 | Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-18 | — | — | US | disclosed |
| US-20060178514-A1 | Novel benzylamine derivatives as CETP inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-08-10 | — | — | US | disclosed |
| WO-2006073973-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |