SCHEMBL562596

SCHEMBL562596

CCC(C)(C)c1ccc(-c2c(OP(Oc3ccc(C(C)(C)CC)c(-c4ccc(C(C)(C)CC)cc4C(C)(C)CC)c3-c3ccc(C(C)(C)CC)cc3C(C)(C)CC)Oc3ccc(C(C)(C)CC)c(-c4ccc(C(C)(C)CC)cc4C(C)(C)CC)c3-c3ccc(C(C)(C)CC)cc3C(C)(C)CC)ccc(C(C)(C)CC)c2-c2ccc(C(C)(C)CC)cc2C(C)(C)CC)c(C(C)(C)CC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
NPSR1 Q6W5P4 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 5/20 0.42
HTT P42858 3/20 0.42
UBE2N P61088 2/20 0.42
GLA P06280 1/20 0.42
MITF O75030 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
LMNA P02545 1/20 0.38
CASP3 P42574 1/20 0.38
ATM Q13315 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
RAD52 P43351 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561156 0.90 MAPK1 (0.43) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL29489559 0.90 MAPK1 (0.43) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL16394087 0.83 MAPK1 (0.39) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL29443083 0.82 MAPK1 (0.54) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL133717 0.82 MAPK1 (0.54) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL561407 0.77 CA1 (0.33) MAPK1NPSR1ALDH1A1MAPTRAB9A
SCHEMBL29760902 0.76 MAPK1 (0.48) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL798770 0.76 MAPK1 (0.48) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL29760889 0.76 MAPK1 (0.48) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL798108 0.76 MAPK1 (0.48) MAPK1SMN1; SMN2NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230108018-A1 Hydrolytically Stable Phosphite Composition, Polymer Composition Comprising Said Hydrolytically Stable Phosphite Composition SI GROUP, INC. 2023-04-06 US claimed
EP-4118140-A1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITION, POLYMER COMPOSITION COMPRISING SAID HYDROLYTICALLY STABLE PHOSPHITE COMPOSITION SI Group-Switzerland GmbH (CH) 2023-01-18 EP claimed
WO-2021180834-A1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITION, POLYMER COMPOSITION COMPRISING SAID HYDROLYTICALLY STABLE PHOSPHITE COMPOSITION SI Group Switzerland (Chaa) Gmbh (CH) 2021-09-16 WO claimed
US-20180244898-A1 COMPOSITION SI GROUP USA (USAA), LLC 2018-08-30 US claimed
EP-3344693-A1 COMPOSITION Addivant Switzerland GmbH (CH) 2018-07-11 EP claimed
EP-2459574-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2018-06-20 EP claimed
WO-2017037205-A1 COMPOSITION ADDIVANT SWITZERLAND GMBH (CH) 2017-03-09 WO claimed
EP-2057222-B2 COMPOSITION COMPRISING LIQUID PHOSPHITE BLENDS AS STABILIZERS ADDIVANT SWITZERLAND GMBH (CH) 2017-03-01 EP claimed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP claimed
EP-2491078-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING Chemtura Corporation (US) 2012-08-29 EP claimed
US-8188170-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-05-29 US claimed
WO-2011049728-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2011-04-28 WO claimed
US-7888414-B2 Liquid phosphite blends as stabilizers CHEMTURA CORPORATION (US) 2011-02-15 US claimed
US-20100197837-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2010-08-05 US claimed
US-20100048782-A1 Liquid phosphite blends as stabilizers SI GROUP, INC. 2010-02-25 US claimed
US-20100004363-A1 LIQUID PHOSPHITE BLENDS AS STABILIZERS CHEMTURA CORPORATION (US) 2010-01-07 US claimed
WO-2025245330-A1 PHOSPHITE POLYMER PROCESSING AID AND PROCESS OF PREPARING A THERMOPLASTIC POLYMER COMPOSITION SI GROUP, INC. (US) 2025-11-27 WO disclosed
US-20250263524-A1 Method for Polycondensation of a Recycled Polyester SI GROUP, INC. 2025-08-21 US disclosed
US-20100025636-A1 LIQUID PHOSPHITE COMPOSITIONS HAVING DIFFERENT ALKYL GROUPS CHEMTURA CORPORATION (US) 2010-02-04 US disclosed
US-20090326112-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2009-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004363-A1 LIQUID PHOSPHITE BLENDS AS STABILIZERS PHOSPHO1, PPA1, PLCG2 MAPK1 3212/4885SMN1; SMN2 231/4885NPSR1 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.