Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5626384 | 0.91 | HPGD (0.41) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| Hydrochloric Acid SCHEMBL5628265 | 0.90 | HPGD (0.42) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| SCHEMBL5628972 | 0.88 | AVPR2 (0.48) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| SCHEMBL5629638 | 0.86 | AVPR2 (0.46) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| SCHEMBL5626957 | 0.80 | AVPR1A (0.42) | AVPR2SLC6A7ALDH1A1LMNAHTR2B | |
| SCHEMBL5627644 | 0.79 | NAMPT (0.44) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| SCHEMBL5626780 | 0.79 | TSHR (0.45) | AVPR2SLC6A7HTR2BMGLLAVPR1A | |
| SCHEMBL5626594 | 0.78 | AVPR1A (0.47) | AVPR2SLC6A7ALDH1A1LMNARAD52 | |
| SCHEMBL5626277 | 0.78 | AVPR1A (0.48) | AVPR2SLC6A7ALDH1A1HTR2BAVPR1A | |
| SCHEMBL5626387 | 0.78 | EPHX2 (0.42) | AVPR2SLC6A7ALDH1A1LMNARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202239-B2 | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH (US) | 2007-04-10 | — | — | US | claimed |
| US-7202239-B2 | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1377582-A1 | NOVEL 3-C(O)R SUBSTITUTED 10-CYCLOHEXYLBENZOYL PYRROLOBENZODIAZEPINES; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Wyeth (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002085907-A1 | NOVEL 3-C(O)R SUBSTITUTED 10-CYCLOHEXYLBENZOYL PYRROLOBENZODIAZEPINES; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH (US) | 2002-10-31 | — | — | WO | disclosed |