Indoline

Indoline

SCHEMBL5629

c1ccc2c(c1)CCN2

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indoline SCHEMBL29360339 1.00
Indoline SCHEMBL1085136 0.97 HTR2C (0.50)
Indoline SCHEMBL10723456 0.97 HTR2C (0.50)
Indoline SCHEMBL3905169 0.97 HTR2C (0.50)
Indoline SCHEMBL1587228 0.97 HTR2C (0.50)
Indoline SCHEMBL23295083 0.97 HTR2C (0.50)
Indoline SCHEMBL6872936 0.97 HTR2C (0.50)
Indoline SCHEMBL8194348 0.97 HTR2C (0.50)
Indoline SCHEMBL4903255 0.97 HTR2C (0.50)
Indoline SCHEMBL11401846 0.97 HTR2C (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 76340 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US claimed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP claimed
CN-117886736-B 2-Indolyl-3-imine indoline derivative, preparation method and application thereof Suzhou Highfine Biotech Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-108290955-B Humanized anti-CLL-1 antibodies UK Medical Ltd. (IE) 2026-05-26 CN claimed
CN-122057522-A Nickel-based catalyst based on bi-metal solid solution oxide as carrier, preparation method and application thereof in hydrogen production 吉林大学 2026-05-19 CN claimed
WO-2026098527-A1 COMPOUND AND USE THEREOF IN PREPARATION OF ANTI-INFLAMMATORY DRUG 中国人民解放军陆军军医大学 2026-05-15 WO claimed
CN-119707970-B Method for synthesizing indoline derivative by palladium-catalyzed asymmetric hydrogenation 中国科学院大连化学物理研究所 2026-05-15 CN claimed
CN-116145156-B Indoline compound preparation method based on organic electronic synthesis 六盘水师范学院 2026-05-15 CN claimed
CN-122005558-A Compound serving as AKR1C3 inhibitor as well as preparation method and application thereof 广州医科大学 2026-05-12 CN claimed
US-4090845-A WATER SOLUBLE QUATERNARY AMMONIUM COMPOUNDS AS RETARDANT-LEVELLING AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-05-23 US claimed
US-4087442-A CYCLIZATION OF O-HALOGENO-PHENETHYLAMINE, COPPER TYPE CATALYST AND AMMONIA IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1978-05-02 US claimed
US-4087247-A CATIONIC DYES, WATER SOLUBLE QUATERNARY AMMONIUM SALT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-05-02 US claimed
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US claimed
US-4032346-A 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US claimed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 US claimed
US-3984246-A MONO-, TRI-, OR PENTAMETHINE OXONOLES OF 1-SULFOLANYL PYRAZOLONES AGFA-GEVAERT, A.G. (DT) 1976-10-05 US claimed
US-3981869-A BENZOTHIAZOLE, BENZOXAZOLE AND INDOLE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US claimed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US claimed
US-3935199-A ANALEPTIC MEAD JOHNSON & COMPANY (US) 1976-01-27 US claimed