Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.82 |
| ▸ | F2 | P00734 | 2/20 | 0.80 |
| ▸ | F11 | P03951 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436287 | 1.00 | F10 (0.82) | F10F2F11 | |
| SCHEMBL5432629 | 0.90 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14490791 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL2168242 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14490683 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14490792 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14502286 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL5447299 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14490670 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL1999238 | 0.89 | F10 (1.00) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |