Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.30 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | RARG | P13631 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630779 | 1.00 | RECQL (0.31) | RECQLTP53HTTRARARARB | |
| SCHEMBL5628556 | 0.91 | OPRL1 (0.30) | OPRL1 | |
| SCHEMBL5628547 | 0.91 | OPRL1 (0.30) | OPRL1 | |
| SCHEMBL5627792 | 0.85 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL5627797 | 0.85 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL5628832 | 0.84 | MRGPRX4 (0.33) | TP53HTTOPRL1 | |
| SCHEMBL5628822 | 0.84 | MRGPRX4 (0.33) | TP53HTTOPRL1 | |
| SCHEMBL5629225 | 0.82 | TP53 (0.32) | TP53HTTOPRL1 | |
| SCHEMBL5628394 | 0.82 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL5629230 | 0.82 | TP53 (0.32) | TP53HTTOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | claimed |
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | disclosed |
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | disclosed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | CYP51A1, DPM1, GMDS | RECQL 3558/4885TP53 4639/4885HTT 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.