Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.80 |
| ▸ | F2 | P00734 | 3/20 | 0.79 |
| ▸ | F11 | P03951 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432478 | 1.00 | F10 (0.80) | F10F2F11 | |
| SCHEMBL14490785 | 0.89 | F10 (1.00) | F10F2F11 | |
| SCHEMBL2167736 | 0.88 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14524989 | 0.88 | F10 (1.00) | F10F2F11 | |
| SCHEMBL5629840 | 0.88 | F10 (1.00) | F10F2F11 | |
| SCHEMBL14490787 | 0.87 | F10 (1.00) | F10F2F11 | |
| SCHEMBL5431971 | 0.86 | F10 (0.86) | F10F2F11 | |
| SCHEMBL5430392 | 0.86 | F10 (0.85) | F10F2F11 | |
| SCHEMBL5631086 | 0.86 | F10 (0.85) | F10F2F11 | |
| SCHEMBL2168020 | 0.84 | F10 (1.00) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |