SCHEMBL5632476

SCHEMBL5632476

CC(C#Cc1cccc(C#CC(C)=CCO)c1)=CCO

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.52
FFAR4 Q5NUL3 2/20 0.38
CHRM2 P08172 6/20 0.37
CHRM1 P11229 5/20 0.37
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35
NR1H3 Q13133 1/20 0.35
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5632474 1.00 FFAR1 (0.52) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5486388 0.87 FFAR1 (0.50) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5480906 0.87 FFAR1 (0.50) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5480902 0.87 FFAR1 (0.50) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5484146 0.85 FFAR1 (0.47) FFAR1FFAR4PPARA
SCHEMBL5634911 0.84 FFAR1 (0.54) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5634910 0.84 FFAR1 (0.54) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL9440070 0.80 FFAR1 (0.45) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5634669 0.79 FFAR1 (0.50) FFAR1FFAR4CHRM2CHRM1PPARD
SCHEMBL5634667 0.79 FFAR1 (0.50) FFAR1FFAR4CHRM2CHRM1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220877-B2 Compounds, their preparation and use NOVO NORDISK A/S (DK) 2007-05-22 US disclosed
EP-1438283-A1 DICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE NOVO NORDISK A/S (DK) 2004-07-21 EP disclosed
US-20030109579-A1 Novel compounds, their preparation and use HIGH POINT PHARMACEUTICALS, LLC 2003-06-12 US disclosed
WO-2003033453-A1 DICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109579-A1 Novel compounds, their preparation and use PPARG, PPARA, PPARD FFAR1 33/4885FFAR4 36/4885CHRM2 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.