Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | CASP7 | P55210 | 10/20 | 0.47 |
| ▸ | CASP1 | P29466 | 9/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | WEE1 | P30291 | 4/20 | 0.46 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | GLA | P06280 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511668 | 0.86 | SRC (0.62) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5633975 | 0.76 | FGFR1 (0.60) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5523042 | 0.75 | SRC (0.74) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5520408 | 0.73 | FGFR1 (0.64) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5523958 | 0.70 | FGFR1 (0.58) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5516295 | 0.67 | FGFR1 (0.56) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL5534904 | 0.65 | CYP1A2 (0.74) | CYP1A2ALDH1A1CASP7CASP1HIF1A | |
| SCHEMBL3458816 | 0.62 | SRC (1.00) | WEE1SRCFGFR1PDGFRBSLC2A1 | |
| SCHEMBL29508114 | 0.62 | SRC (1.00) | WEE1SRCFGFR1PDGFRBSLC2A1 | |
| SCHEMBL5524754 | 0.60 | SRC (0.74) | CYP1A2ALDH1A1CASP7CASP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169778-B2 | Pteridinones as kinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2007-01-30 | — | — | US | claimed |